In 1937, Huxley moved to Hollywood, CA with his wife Maria and their son Matthew and earned some income as a writer. In March 1938, his friend Anita Loos, a novelist and screenwriter, put him in touch with Metro-Goldwyn-Mayer who hired Huxley for Madame Curie which was originally to star Greta Garbo and be directed by George Cukor. (The film was eventually completed by MGM in 1943 with a different director and cast.) Huxley received screen credit for Pride and Prejudice (1940) and was paid for his work on a number of other films, including Jane Eyre (1944).
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However, his success in Hollywood was minimal. When he wrote a synopsis of Alice in Wonderland, Walt Disney rejected it on the grounds that "he could only understand every third word". Huxley's leisurely development of ideas, it seemed, was not suitable for the movie moguls, who demanded fast, dynamic dialogue above all else. For Dick Huemer, during the 1940s, Huxley went to the first of a five meetings' session to elaborate the script of Alice in Wonderland but never came again. For author John Grant, although the movie's character the Caterpillar displays some characteristics familiar from Huxley's discussion of his experiments with hallucinogens, Huxley's contribution to the movie is nonexistent.
Huxley lived in the U.S., mainly in southern California, until his death on 22 Nov 1963.